Composite resins: a review of adhesive failure from enzymatic degradation

Aim: This study aims to review the concepts and metalloproteinase activation mechanisms and cathepsin cysteine. Material and Methods: The literature review was conducted around the main keywords "cathepsin cysteine", "metalloproteinases", "dentin-adhesive interface" and "degradation". Results: Nineteen articles were collected and included only articles available in its entirety, on english. Conclusions: Many studies are still being conducted incorporating different substances that help by inhibiting the action of these enzymes, however, there is still no consensus on the best element to be used in restorative procedures.